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Jessica Goldstein, born in 1969, grew up in the Homewood community of Birmingham, Alabama. As a child, she attended temple at Knesseth Israel with her family. Every Friday, her mother prepared gelfite fish, soup, and challah bread for Shabbat dinner. Goldstein attended college in Israel, studying anthropology and linguistics at the University of Tel Aviv.
She returned to the United States to study nursing. Goldstein has worked both in nursing and in the medical research field. She currently works for the American Society for Reproductive Medicine. Her family now attends Temple Beth-El in Birmingham and she continues to celebrate Shabbat dinners every Friday night with varying menus and a community of friends and family.